Relegation-battling Norwich City face a tough test as they welcome top four-chasing Leicester City to Carrow Road in Friday Night Football from the Premier League.
Coventry City take on Sunderland at the St Andrew's Trillion Trophy Stadium in the Sky Bet Championship. A last-minute strike saw the Black Cats win 2-1 earlier in the season.
Brighton host rivals Crystal Palace at the AMEX Stadium as they meet in the Premier League.
Hull City welcome Marcelo Bielsa's Leeds United to the KCOM Stadium in the Sky Bet Championship. The Whites were 2-0 winners when the sides met earlier in the season.
Nigel Pearson's Watford welcome title-chasing Liverpool to Vicarage Road in the Premier League. A Mohamed Salah brace was enough to see the Reds over the lines in the reverse game.
Carlo Ancelotti's Everton take on Manchester United at Goodison Park in the Premier League. The sides shared the spoils in a 1-1 draw in the reverse fixture.
It all comes down to this: Aston Villa and Manchester City go toe-to-toe for the first silverware of the season in the Carabao Cup final at Wembley. City are the current holders.
Hoping to earn a spot in the quarter-finals, Arsenal travel to Fratton Park to take on League One side Portsmouth in the fifth round of the FA Cup.